Propolis supplementation affects performance, intestinal morphology, and bacterial population of broiler chickens

A meta-analysis was conducted to examine the effect of supplementing diet broiler chickens with propolis on growth, bacterial population intestine, antiviral serum concentration, intestinal morphology, and digestive enzyme activities in chickens. Forty peer-reviewed articles that had been published between 2003 2019 were identified using PRISMA protocol included study. Data analysed mixed model methodology, which studies considered random effects, whereas level supplemental a fixed effect. Responses supplementation bodyweight (BW) average daily gain (ADG) quadratic, but feed intake (ADFI) not affected. Propolis improved conversion ratio (FCR) significantly as linear function supplement. The optimum 256 262 mg/kg produced maximum ADG final BW. There tendency for mortality decrease because supplementation. no detectable or morphology. Among enzymes, only sucrase increased linearly increased. Thus, growth performance positively dose dependent. This may have partly an improvement activity other factors related nutritional content propolis. Future study evaluate specific bioactive compounds is therefore warranted.